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Thats especially true if youre a little older, or if you have less collagen due to your genetics or time spent in the sun

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In my own case, as Im sure plenty can relate to, it felt like life was just piling the weight onto me

A disrupted vascular endothelium has slow blood flow and/or harbors generated vortexes, with the platelet hyperfunction susceptible to thrombosis, resulting in ischemia in vital organs

However, a proteasome-independent mechanism might also contribute to CIPN